Short Communication PPAR Mediates a Direct Antiangiogenic Effect of 3-PUFAs in Proliferative Retinopathy
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Comparison of axial length of the eye in patients with diabetic retinopathy and non diabetics
Introduction: To compare the axial length of globe in patients with diabetic retinopathy with that in normal population and to evaluate its role in the progression of diabetic retinopathy. Methods: 150 patients with diabetic retinopathy in both eyes were compared with 150 age and sex matched non diabetic patients, referred to Motahari retina clinic of Shiraz, during fall 2000. The axial length...
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Although cellular and molecular bases of proliferative diabetic retinopathy are only partially understood, it is evident that this complication of diabetes is characterized by the formation of new vessels inside the retina showing abnormal architecture and permeability. This process, if not controlled by selective laser photocoagulation, leads to irreversible retinal damages and loss of vision....
متن کاملAntiangiogenic drugs and advanced proliferative diabetic retinopathy Drogas antiangiogênicas em retinopatia diabética proliferativa avançada
Advanced diabetic retinopathy with vitreous hemorrhage or tractional retinal detachment (TDR) is an important cause of severe visual loss in patients with proliferative diabetic retinopathy (PDR), frequently representing an indication for pars plana vitrectomy in diabetic patients. In these cases, surgery is not free from complications such as intraoperative vitreous hemorrhage and retinal rupt...
متن کاملAssociation of CXCL12 and CXCR4 Genes Polymorphism with Proliferative Diabetic Retinopathy in Diabetic Patients
Introduction: Patients with diabetes are prone to develop complications related to the retina. So far, several genes have been reported in connection with the progression of retinopathy, and a group of these genes is genes involved in angiogenesis. CXCL12 and CXCR4 genes are among the most important genes in this path, which have been less studied and investigated. The aim of this study was to ...
متن کاملA peptide derived from type 1 thrombospondin repeat-containing protein WISP-1 inhibits corneal and choroidal neovascularization.
PURPOSE Ocular neovascularization is the primary cause of blindness in a wide range of prevalent ocular diseases including proliferative diabetic retinopathy, exudative age-related macular degeneration, and retinopathy of prematurity, among others. Antiangiogenic therapies are starting to give promising results in these diseases. In the present study the antiangiogenic potential of an 18-mer pe...
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تاریخ انتشار 2010